Digitalization of society: implications and perspectives in the context of the psycho-dimensionality of social reality / psychosynertics

The purpose of this article is to analyze the process of «digitalization» of modern society from the point of view of psychosynergistic approach, psycho-dimensionality of social reality as subjective association of people. The concept of «digitalization» is used mainly in scientific and philosophical publications where it is presented as a modern «world trend». The concept of «digitization» is associated with profound changes in the social life of a modern person who in the near future will be in a fully digital world where every aspect of his life will be deeply influenced by digital data: how people will communicate and relate to each other; how they will work, learn, stay healthy and participate in politics and the economy. The introduction of digital technologies promises, on the one hand, enormous benefits for better health, more efficient social mobility, more efficient use of energy, more business and more prosperous companies, etc. But it is also obvious that such a fundamental social transformation will have certain complexities of an individual, intra-psychic nature, i.e. that unexpected challenges and problems that did not exist before have already arisen and may arise further. The main theoretical base of the research are scientific and philosophical publications devoted to the problem of «digitization» and its influence on social life in English and Ukrainian languages. In the works of Ukrainian researchers, attention is mainly paid to economic and technological aspects of «digitalization», but we propose to solve this problem with transdisciplinary approach in which the efforts of scientists from different fields of knowledge (humanities, doctors, psychologists, representatives of computer sciences, etc.) will find general recommendations and regulations, which will help to adapt the person in new social conditions «digital society». One such transdisciplinary area could be psychosynergetics, as a post-non-classical area of knowledge that implements synergistic and other ideas. &nbsp

Polymorphism of gene glutathion-s-transferase pi in teenagers from Buryat ethnic group living in the Irkutsk region

Background. Human glutathione-S-transferases play an important role in phase II detoxification process. But polymorphism in the GSTP1 gene has not been studied in certain populations. Aim: to determine the distribution of allele and genotype frequencies of GSTP1 gene in teenagers from Buryat ethnic group. Materials and methods. Blood samples were obtained from 55 teenagersfrom Buryat ethnic group. There were 28 males and 27 females with an age of 14.05 ± 0.99 years over the range of 13 to 16. DNA was isolated from blood samples. The polymerase chain reaction was used to amplify A313G and C341T markers of the GSTP1 gene. Chi-square testing was used to evaluate the significant difference of the GSTP1 genotype frequencies between observed and expected values. Results. Allele and genotype frequencies of A313G and C341T markers GSTP1 were determined in teenagers from Buryat ethnic group. The study showed that the frequencies of A and G alleles at the A313G marker were 0.809 and 0.191 while those of C and T alleles at the C341T marker were 0.973 and 0.027, respectively. The distribution of the genotype frequencies at the A313G marker were consistent with expected in a Hardy - Weinberg equilibrium (χ2 = 0.77; d.f. = 1; p > 0.05). However, the distribution of the genotype frequencies at the C341T marker were not consistent with expected in a Hardy - Weinberg equilibrium (χ2 = 0.043; d.f. = 1; p < 0.05). It was because the homozygous of T allele was not found in the ethnic group of Buryat

The research of Subjective Sense of Happiness in Senior Preschoolers

AbstractThe purpose of the study was to examine the perceptions of happiness and to identify the level of subjective happiness among children of senior preschool age. These parameters were studied in their connection with such personal characteristics, as manifestation of extraversion/introversion, anxiety level, willingness to cooperate and the feeling of subjective happiness in mothers of preschoolers. The study found that comparing with children who sometimes feel unhappy, happy children demonstrate a lower anxiety level and a higher degree of extraversion manifestation. Mothers of happy children feel happier than those of children who sometimes feel unhappy

Glutathione S-transferase polymorphism in ethnic groups living in Eastern Siberia

The role of glutathione S-transferase for the life of the cell and the entire organism is related to their participation in the processes of detoxification of xenobiotics and antioxidant protection. Genetic variability of glutathione S-transferases appears in the form of different enzymatic activity of the corresponding protein products. In this study, a comparative analysis was conducted on the frequency of genotypes of three genes in the glutathione S-transferases gene superfamily (GSTM1, GSTT1, GSTP1) from representatives of two ethnic groups, Russian and Buryat. To this end, genetic typing of DNA samples was performed by polymerase chain reaction. Statistically significant differences in the frequency of occurrence of alleles A, B, C of the GSTP1 gene (р = 0.026) were found between the groups of teenagers compared. It was found that the frequency of the allele A, which codes for the active variant enzyme, is significantly higher in the Buryat ethnic group (p = 0.012). The allele B, the product of which is a “slow” version of the enzyme, was significantly more common in the Russian ethnic group (p = 0.014). In the GSTM1 and GSTT1 genes, no statistically significant differences in the frequency of occurrence of “zero” and “functional” genotypes between the compared groups of teenagers were found. However, there was a tendency to increase in the frequency of the “zero” genotype of the GSTM1 gene in the Russian ethnic group. In addition, the frequency of the “zero” genotype in two genes GSTM1 and GSTT1 at once was almost two times higher in the Russian ethnic group than in the Buryat ethnic group

Analysis of depression full-time students

Не только качество образования и профессиональная подготовка, но и здоровье студентов, причем как физическое, так и эмоциональное остается актуальной проблемой для российских университетов, что в свою очередь зависит и от учебного процессаNot only the quality of education and training, but also the health of students, both physical and emotional remains an urgent problem for Russian universities, which in turn depends on the learning proces

СОВРЕМЕННАЯ СИТУАЦИЯ ПО ПАРАЗИТОЗАМ И МЕРЫ БОРЬБЫ С НИМИ В РОССИИ И СТРАНАХ СНГ (по материалам Координационных отчетов)

42 scientific Institutions and High Schools were involved in fulfillment of In- terdepartmental and Interstate programs in 2013. In all regions of Russian Federa- tion and CIS countries were conducted regular monitoring studies on epizootic sit- uation in relation to parasitosis in domestic and wild animals, birds, fish and bees. Based on information system of collecting and analysis of data a monitoring me- thodology of parasitic diseases is elaborated that allows to forecast the develop- ment of epizootic situation and to optimize the struggle against parasitic diseases within particular region. Forecast of epizootic situation on main helminthosis of animals made for 2013 is basically confirmed. Compared to the previous year the epizootic situation got worse in relation to paramphystomatosis in Yakutia, strongi- latosis of gastrointestinal tract and lungs in Southern Siberia and in the Far East as well as in regions infected with eurytremosis and orientobilharciosis. Parasitic fau- na, spread of parasitosis and features of parasitosis course in ruminants (cattle, sheep, goats and deers) are studied on the territory of Moscow, Kalinigrad, Ryasan, Samara and Tyumen regions, Altai, South Ural, North Caucasus, Yakutia, West Kazakhstan, Central and South-Eastern Tajikistan. Features of parasitosis course in carnivorous in Black Earth and Non-Black Earth zones, Krasnodar Krai and Altai are studied. Continuous monitoring studies in regions unfavorable for trichinellosis are being conducted. Features of circulation of trichinellosis in natural biocenosis of Central region of Russia are investigated and methodical guidelines for its pre- vention in hunting farms are developed where a wide range of issues is embraced. A new patented device «Gelmi» is destined for release of eggs and larvae from helminths using peptolysis of muscle tissue samples; a digestion technique for the detection of trichenellosis and opisthorchosis is developed. Furthermore for the first time metacercariae opisthorchis, mesocercariae alaria and larvae of trematodes using a method of peptolysis are released. Techniques for axonomic identifying of genotype of northern isolates of Trichinella spp. on the territory of RF are devel- oped that allows to complete the system characteristic and to detect phylogenetic relationship inside different taxonomic groups. Helminthophauna of predators on the territory of Central Black Earth State Biosphere Reserve are analyzed. Age- related and season infection dynamics are revealed in main commercial fish in Tsimlyansk, Varvarovka, Karpovka reservoirs as well as in Volga and Lena rivers. Monitoring of spread of invasions and infections in honey bees in the South of Tyumen region is conductedПроведен анализ работ научных учреждений и ВУЗов России и стран СНГ, посвященных исследова- ниям в области ветеринарной паразитологии за 2013 г. Изучена паразитофауна, распространение и особенно- сти течения паразитозов у крупного рогатого скота, овец, коз, северных оленей, лошадей, свиней, плотояд- ных, птиц, рыб и пчел на территории России, Белорус- сии, Казахстана, Кыргызстана и Таджикистана. Раз- работаны методы диагностики, профилактики и схе- мы лечения паразитозов. Выявлены особенности им- мунного ответа при паразитозах и их лечении. Созда- ны и испытаны новые комплексные противопарази- тарные препараты, изучены их фармакотоксикологи- ческие свойств

Длительное применение препарата бонвива для лечения постменопаузального остеопороза: новые данные

Osteoporosis is a disease of great social importance. Its treatment is a complicated problem and it is associated with low compliance and a risk for adverse reactions. Ibandronate belongs to a group of bisphosphonates. The performed trials have proven the efficacy of its two formulations (a tablet once monthly and intravenous injection once every 3 months) in reducing the risk of bone fractures. At present there are data of trials of long-term therapy with this drug, which demonstrate its positive effect on bone mineral density and bone metabolism markers. The agent has been also shown to be highly safe when used long.Остеопороз является заболеванием, имеющим большое социальное значение. Его лечение представляет собой сложную задачу и сопряжено с проблемой низкой приверженности пациентов приему препаратов и риском побочных эффектов. Ибандронат относится к группе бисфосфонатов. Проведенные исследования доказали эффективность двух его лекарственных форм (1 таблетка 1 раз в месяц и внутривенная инъекция 1 раз в 3 мес) в отношении снижения риска переломов костей. В настоящее время получены данные исследований длительной терапии этим препаратом, которые демонстрируют его благоприятное влияние на минеральную плотность костной ткани и маркеры костного метаболизма. Кроме того, показана высокая безопасность препарата при длительном использовании

Apolipoprotein-b gen and its role in formation of essential hypertension

For two groups of Russian teenagers the proportion of deletion (Del) allele of the apolipoprotein-B gene polymorphism (ApoB, Ins/Del, rs17240441) was studied. One group of 70 teenagers with essential hypertension, and the comparison group - 73 healthy teenagers. In both groups, the most common genotype was heterozygous genotype Ins/Del, in the group with essential hypertension it was 67,1 %, in the control group - 52,1 %. The frequency of Del allele in the group with essential hypertension was 47,9 %, which was significantly higher than in the comparison group - 30,1 % (p = 0,003). Thus, the high frequency of deletion allele in the studied group with hypertension indicates an increased risk of cardiovascular disease in this group in the future and has prognostic significance

Sampling-based Algorithms for Optimal Motion Planning

During the last decade, sampling-based path planning algorithms, such as Probabilistic RoadMaps (PRM) and Rapidly-exploring Random Trees (RRT), have been shown to work well in practice and possess theoretical guarantees such as probabilistic completeness. However, little effort has been devoted to the formal analysis of the quality of the solution returned by such algorithms, e.g., as a function of the number of samples. The purpose of this paper is to fill this gap, by rigorously analyzing the asymptotic behavior of the cost of the solution returned by stochastic sampling-based algorithms as the number of samples increases. A number of negative results are provided, characterizing existing algorithms, e.g., showing that, under mild technical conditions, the cost of the solution returned by broadly used sampling-based algorithms converges almost surely to a non-optimal value. The main contribution of the paper is the introduction of new algorithms, namely, PRM* and RRT*, which are provably asymptotically optimal, i.e., such that the cost of the returned solution converges almost surely to the optimum. Moreover, it is shown that the computational complexity of the new algorithms is within a constant factor of that of their probabilistically complete (but not asymptotically optimal) counterparts. The analysis in this paper hinges on novel connections between stochastic sampling-based path planning algorithms and the theory of random geometric graphs.Comment: 76 pages, 26 figures, to appear in International Journal of Robotics Researc